Focus tunable lenses

Compact optical design solutions using focus tunable lenses
M. Blum, M. Büeler, C. Grätzel, M. Aschwanden, SPIE Optical Design and Engineering IV, Proceedings Vol. 8167 (2012)

 

Laser speckle reduction

Reduction of coherent artefacts in super-resolution fluorescence localisation microscopy
P. Georgiades, V. J. Allan, M. Dickinson, and T. A. Waight, Journal of Microscopy, 264: 375–383, doi:10.1111/jmi.12453 (2016).

Reducing laser speckle with electroactive polymer actuators
C. Graetzel, M. Suter, M. Aschwanden, Electroactive Polymer Actuators and Devices (EAPAD), Proc. of SPIE Vol. 9430, 943004 (2015).

Speckle reduction with reluctance force-based oscillating diffusors
D. Stadler, M. Suter, M. Ventura, D. Niederer,The 4th Laser Display and Lighting Conference (LDC’15), Yokohama, Japan (2015).

Laser Speckle Reduction based on electroactive polymers
J. Giger, M. Blum, M. Aschwanden, The 1st Advanced Lasers and Photon Sources (ALPS’12), Yokohama, Japan (2012).

 

Applications using Optotune's technology

Microscopy

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser
M. Bathe-Peters, P. Annibale, and M. J. Lohse, Optics Express Vol. 26, Issue 3, pp. 2359-2368 (2018), https://doi.org/10.1364/OE.26.002359

Three-Dimensional Two-Photon Optogenetics And Imaging Of Neural Circuits In Vivo
B.  W. Yang, L. Carrillo-Reid, Y. Bando, D.S. Peterka, R. Yuste, bioRxiv preprint (2017). https://doi.org/10.1101/132506

NeuBtracker—imaging neurobehavioral dynamics in freely behaving fish
B.  P. Symvoulidis, A. Lauri, A. Stefanoiu, M. Cappetta, S. Schneider, H. Jia, A. Stelzl, M. Koch, C. C. Perez, A. Myklatun, S. Renninger, A. Chmyrov, T. Lasser, W. Wurst, V. Ntziachristos, G. G. Westmeyer, Nature Methods - Brief communication (2017). doi:10.1038/nmeth.4459

High-speed dual-layer scanning photoacoustic microscopy using focus tunable lens modulation at resonant frequency
B. K. Lee, E. Chung, S. Lee, T. J. Eom, Optics Express, Vol 22, pp. 26427 (2017). doi.org/10.1364/OE.25.026427

Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy
B. J. N. Singh, T. M. Nowlin, G. J. Seedorf, S. H. Abman, D. P. Shepherd, J. Biomed. Opt., Vol 22, Issue 7, (7), pp. 2035-2046 (2011). doi:10.1117/1.JBO.22.7.076011

Three-dimensional multiple-particle tracking with nanometric precision over tunable axial ranges
B. G. Sancataldo, L. Scipioni, T. Ravasenga, L. Lanzanò, A. Diaspro, A. Barberis, and M. Duocastella, Optica Vol. 4, Issue 3, pp. 367-373 (2017).

Reduction of coherent artefacts in super-resolution fluorescence localisation microscopy
A. P. Georgiades, V. J. Allan, M. Dickinson, T. A. Waight, Journal of Microscopy (2016); doi: 10.1111/jmi.12453

Correction-free remotely scanned two-photon in vivo mouse retinal imaging
A. Schejter Bar-Noam, N. Farah & S. Shoham, Light: Science & Applications (2016) 5, e16007; doi:10.1038/lsa.2016.7

High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes
Y. Nakai, M. Ozeki, T. Hiraiwa, R. Tanimoto, A. Funahashi, N. Hiroi, A. Taniguchi, S. Nonaka, V. Boilot, R. Shrestha, J. Clark, N. Tamura, V. M. Draviam and H. Oku, Rev. Sci. Instrum. 86, 013707 (2015).

Multi-depth photoacoustic microscopy with a focus tunable lens
Kiri Lee, Euiheon Chung, Tae Joong Eom, Proc. of SPIE Vol. 9323 93233O-1 (2015)

Calcium transient prevalence across the dendritic arbour predicts place field properties
M. E. J. Sheffield, D. A. Dombeck, Nature 517, 200–204 (2015).

3d high- and superresolution imaging using single-objective SPIM
Remi Galland et al., Nature Methods 3402, 1-4 (2015)

Fast imaging of live organisms with sculpted light sheets
A. K. Chmielewski, A. Kyrsting, P. Mahou, M. T. Wayland, L. Muresan, J. F. Evers & C. F. Kaminski, Scientific Reports 5, Article number: 9385 doi:10.1038/srep09385 (2015).

A rapid image acquisition method for focus stacking in microscopy
D. Clark, B. Brown, Microscopy Today, Volume 23, Issue 04, pp 18-25 (2015)

Rapid quantitative phase imaging for partially coherent light microscopy
B. José A. Rodrigo and Tatiana Alieva, Optics Express, Vol. 22, Issue 11, pp. 13472-13483 (2014).

Investigation of diffraction-based measurement errors in optical testing of aspheric optics with digital micromirror devices
Stephan Stuerwald, Robert Schmitt, J. Micro/Nanolith. MEMS MOEMS 13(1), 1-8, (2014)

Technical improvements applied to a double-pass setup for performance and cost optimization
Ferran Sanabria et al., Optical Engineering 53(6), 061710 (2014)

Improved quantitative phase contrast in self-interference digital holographic microscopy and sensing dynamic refractive index changes of the cytoplasm using internalized microspheres as probes
B. Kemper, R. Schubert, S. Dartmann, A. Vollmer, S. Ketelhut, G. von Bally, SPIE Three Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XX, Proceedings Vol. 8589 (2013).

Rapid 3D light-sheet microscopy with a tunable lens
F. O. Fahrbach, F. F. Voigt, B. Schmid, F. Helmchen, J. Huisken, Optics Express, Vol. 21, Issue 18, pp. 21010-21026 (2013).

Online correction of licking-induced brain motion during two-photon imaging with a tunable lens
J. L. Chen, O. A. Pfäffli, F. F. Voigt, D. J. Margolis, F. Helmchen, Journal of Physiology, 00.00, pp. 1-10 (2013).

High-speed transport-of-intensity phase microscopy with an electrically tunable lens
C. Zuo, Q. Chen, W. Qu, and A. Asundi, Optics Express, Vol. 21, Issue 20, pp. 24060-24075 (2013).

Notch spatial filtering of image artifacts for structured illumination microscopy of cell-based assays
Jong-ryul Choi, Donghyun Kim, Optics Communications 308 (2013) 142–146 (2013)

Fast two-layer two-photon imaging of neuronal cell populations using an electrically tunable lens
B. F. Grewe, F. F. Voigt, M. van't Hoff, F. Helmchen, Biomedical Optics Express, Vol. 2, Issue 7, pp. 2035-2046 (2011).

 

Optical Coherence Tomography (OCT)

Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye
I. Grulkowski, S. Manzanera, L. Cwiklinski, F. Sobczuk, K. Karnowski, and Pablo Artal, Optica, Vol. 5, Issue 1, p.52-59 (2018)

Microscope-integrated intraoperative OCT with electrically tunable focus and heads-up display for imaging of ophthalmic surgical maneuvers
B. Y. K. Tao, S. K. Srivastava, J. P. Ehlers, Biomedical Optics Express, Vol. 5, Issue 6, pp. 1877-1885 (2014).

 

Other applications

Synthetic three-dimensional atomic structures assembled atom by atom
D. Barredo, V. Lienhard, S. de Léséleuc, Th. Lahaye, and A. Browaeys, arXiv:1712.02727 [quant-ph] (2017)

Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery
D. Volpi, I. D. C. Tullis, P. R. Barber, E. M. Augustyniak, S. C. Smart, K. A. Vallis, and B. Vojnovic, Biomedical Optics Express Vol. 8, Issue 7, pp. 3232-3247 (2017)

Optimizing virtual reality for all users through gaze-contingent and adaptive focus displays
N.Padmanaban, R. Konrad, T. Stramer, E. A. Cooper, G. Wetzstein, PNAS (2017)

Novel Optical Configurations for Virtual Reality: Evaluating User Preference and Performance with Focus-tunable and Monovision Near-eye Displays
R. Konrad, E. A. Cooper, G. Wetzstein, (2016)

Dynamic lens and monovision 3D displays to improve viewer comfort
P. V. Johnson, J. A.Q. Parnell, J. Kim, C. D. Saunter, G. D. Love, M. S. Banks, arXiv:1512.09163 (2015)

Optical transport of ultracold atoms using focus-tunable lenses
J. Léonard, M. Lee, A. Morales, T. Karg, T. Esslinger, T. Donner, New J. Phys. 16093028 (2014).

Spherical refractive correction with an electro-optical liquid lens in a double-pass system
P. F. Sanabria, F. Diaz-Douton, M. Aldaba, J Pujol, J. Europ. Opt. Soc. Rap. Public. 8,13062 (2013)

Measurement of the M2 beam propagation factor using a focus-tunable liquid lens 
R. D. Niederriter, J. T. Gopinath, M. E. Siemens, Applied Optics, Vol. 52, Issue 8, pp. 1591-1598 (2013).

Focal Sweep Videography with Deformable Optics
D. Miau, O. Cossairt, and S. K. Nayar, IEEE International Conference on Computational Photography (ICCP) (2013)

Simulation and realization of a focus shifting unit using a tunable lens for 3D laser material processing 
G. Eberle, V. Chiron, K. Wegener,  Lasers in Manufacturing Conference, Munich, Germany (2013).